Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
1)Thank You: Common courtesy? Sure. But tell me this: When was the last time you forgot (or rejected) gratitude? Whether given in private or public, a sincere ‘thanks’ creates goodwill. Don’t forget your mother’s advice: “Say please.” People are always happier doing a favor than taking an order.
Two against-the-clock tours of Los Angeles. Two celebrations of the sometimes prickly solidarity among women. Four tremendous performances, from Kitana Kiki Rodriguez, Mya Taylor, Julia Garner and the great Lily Tomlin. “Grandma” is the work of a studio veteran. “Tangerine” was shot on iPhones. Anyone prone to lamenting the death of movies needs to shut up and watch these.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
The first view is that the price is inherently cyclical. What has come down must go back up again and the deeper the trough the higher the next mountain.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
最佳乐队组合：Little Big Town
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
The media are annoying, we get that, Your Royal Highness, but there may have been more dignified ways for you (and the establishment you represent) to air your concerns.
Trends and targets in antiviral phototherapy
Nirvana in Fire
She says she noticed the similarities between her and the Disney character when she first saw the film in December, calling the experience eerie.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
One side of the capsized Eastern Star was rolled above water at 7:30 am Friday, as rescuers worked through the night to right the upturned ship in the Yangtze River. The side that has emerged shows "Eastern Star" in Chinese character on the hull.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Wang Jie, the general manager of a Beijing-based investment company, said the higher pay for executives in the financial and real estate industries shows the imbalance of development in China.
ACE2 as a potential therapeutic target for pandemic COVID-19
Having said this, don't make a pest of yourself. Nobody wants to hear you ask a question every 10 minutes. If you're completely lost, make an appointment to see your teacher after class.
Diagnostic technologies for COVID-19: a review
Take multiple measures to cut costs.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
The 500 brands come from 28 different countries, among which nearly half, 227, are from the US.
The result doesn't look much like a nose—it's a bottle filled with liquid nutrient that cultivates bacteria. But give the “nose” a blood sample and let it sniff for a few days, and the bottle's dots will change color to indicate what bacteria, if any, it identifies.
The United Kingdom ranks No. 3 overall. It ranks No. 4 in Power and No. 5 in Cultural Influence.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Founded in the 5th century and covering 118 small islands, the Northeast Italian city is famed for its water views, architecture and artwork.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Chris Washington, played by London-born Daniel Kaluuya, is drawn into the sinister underbelly of a small American community.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
The disclosure form also warns forex buyers that they are not allowed to exploit others’ exchange quotas. Previously, aggregating quotas from multiple individuals was a common technique that grey-market money changers used to obtain large sums of foreign exchange.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Chinese property magnate Wang Jianlin has defended his crown as the country's richest man, according to the annual Hurun rich list, fending off Alibaba Group Holding Ltd (BABA.N) founder Jack Ma and new players on the block like Baoneng's Yao Zhenhua.
Only three Hollywood productions, 'Furious 7', 'Avengers: Age of Ultron', and 'Jurassic World', made it into the top 10 at the Chinese box office in 2015.
The region boasts hundreds of miles of beaches and lakeshore, some of the country's oldest forests and waterfalls. Best of all, it offers reasonable travel costs and sees far fewer travelers than big cities.
《火线警探》，FX，1月20日。副警长瑞兰·吉文斯（Raylan Givens，蒂莫西·奥利芬特[Timothy Olyphant]饰）与他的朋友兼天敌博伊德·克劳达（Boyd Crowder，沃尔顿·戈金斯[Walton Goggins]饰）之间爱恨交织的关系贯穿了整部剧，不管怎样，这个问题将在第六季，也就是最终季中得到最终解决。
Influenza neuraminidase: A druggable target for natural products
There are 15 Chinese brands in the top 100, one more than last year and a sharp rise on a decade ago, when China Mobile was the only Chinese brand.
The ability of customers to air their dirty laundry to the world via Twitter and Facebook has already changed the customer service game. A 2012 Nielsen survey shows more than half of all customers now turn to social media for redress; meanwhile, some 81% of Twitter users expect a same-day response to questions and complaints. But this fall, things got even more interesting: On Sept. 2, British Airways passenger Hasan Syed spent an estimated $1,000 to purchase several promoted Tweets blasting the company for losing luggage. With paid social media now in customers' arsenal, 2014 may mark the beginning of the end of abysmal customer service at major airlines, credit card companies, banks, and other repeat offenders, characterized by endless phone wait times and those automated "phone trees" (i.e., "Press 1 for English, 2 for Spanish, 3 to waste your entire afternoon on hold ...").
Brazil lost that 1950 final, 2-1, to Uruguay, a historic humiliation that still stings Brazilian fans today. Belmonte, 85, hopes he'll get to see his country regain its honor. "I hope Brazil will be able to win this time," he said. "This is our revenge. I want to go see our revenge."
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
In 2016, 1,576 foreigners became permanent Chinese residents, an increase of 163% on the previous year, according the Ministry of Public Security.
The role of biosensors in the detection of emerging infectious diseases
In May 1940, Germany advanced into France, trapping Allied troops on the beaches of Dunkirk. Under air and ground cover from British and French forces, troops were slowly and methodically evacuated from the beach using every serviceable naval and civilian vessel that could be found. At the end of this heroic mission, 330,000 French, British, Belgian and Dutch soldiers were safely evacuated.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
The Dutch case involved sophisticated financial professionals, people accustomed to analyzing financial and economic trends. Yet, they too focused on their personal experience.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Businesswomen are booming in Asia: The whole region makes a strong showing, from China and Singapore to New Zealand and Thailand. Entrepreneurship is on the rise: see Zhang Xin (No. 50) , Sun Yafang (No. 77) and Solina Chau (No. 80). And Asian region women are showing their political might, from newcomer Park Geun-hye, the South Korean president (No. 11) and Burmese dissident and parliamentarian Aung San Suu Kyi (No. 29) to Australian PM Julia Gillard (No. 28) and Thai Prime Minister Yingluck Shinawatra (No. 31).
在所有这些影片中，斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿，包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
"As robotics is expanding into nearly every industry, Chinese robot makers should realize the gap between them and foreign brands, take advantage of China's robotics development boom and learn from foreign experience to help China grow from the world's largest robot market into a robot manufacturing power," said Qu.
Big-spending US firms are forcing their UK counterparts to increase salaries right the way from newly qualifieds to the top rainmakers — though that did not stop David Higgins, private equity star at Freshfields, from decamping to Kirkland & Ellis just before Christmas. Boutique specialists are luring clients away by offering faster, more focused services.
And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Jose's mother Inma Quesada told the El Pais daily that her son "wanted to buy instruments" for his band Los Salerosos (loosely translated as "The Salties"), in which he plays the trumpet.
Inhibition of SARS coronavirus helicase by bismuth complexes
Trade flows brought China’s balance of trade to $40.82bn, roughly $7.2bn below expectations and down about $3.6bn from November’s revised level of $44.23bn (previously $44.61bn). That balance came to Rmb275.4bn in local-currency terms.
Benmosche's abrasive morale-building exercise at AIG will take hold. The U.S. pay czar will give Benmosche leeway on pay. And a continuing rebound in the markets will give AIG a shot at repaying a good chunk of taxpayer money.
Some Brexiters and Republicans believe in the ideal of absolutely free markets.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
3.Sit in the Front Row
She only learnt to walk five months ago, but 'Baby Beyoncé' is already strutting her stuff on stage at pageants.
BEST THROWING TOYS OUT OF PRAM
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
The show is iconic among those who grew up in the 1990s because it explores core themes like friendship, struggling to survive in a big city, and finding independence and identity, all of which are still relevant to young audiences today.
This year's new college grads entering the workforce are being offered an average monthly salary of 4,014 yuan ($582), and about one-third of them chose to work in first-tier cities, according to survey results released by zhaopin.com, a Chinese online recruitment service provider.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Barack Obama went on the offensive over foreign policy in the third and final presidential debate, repeatedly accusing Mitt Romney of flip-flopping on major international issues but failing to deliver a killer blow to his opponent's resurgent campaign.
We will continue to encourage people to start businesses and make innovations.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
It is estimated that over 89m enterprise retirees and more than 17m institution retirees will benefit from the adjustment.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
On questions 10 and 11, if you circled 0, enter 4; if 1, enter 3; if 2, enter 2; if 3, enter 1; if 4, enter 0.
James Bond Themes 8. "You Only Live Twice" by Nancy Sinatra
2. The new one childplus policy will substantially raise the birth rate, contributing up to 2million new children to the 2014 economy, a 15 percent one-year lift that willonly further boost consumer morale and spirit.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The pipelines were building in spite of poor performance for this year’s high-profile deal from Snap, the owner of Snapchat, in the US and investor concerns that a strengthening euro may curtail the earnings recovery in Europe.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
It was 8.9% in 2015 and 9.9% in 2014. The expenditure accounted for 2.11% of last year's total GDP, compared with 2.06% in 2015.
10. 《66》(Sixty Six)。刘易斯·卡尔(Lewis Klahr)把数码短片精彩地汇集在一起，以一种英雄气概的方式复制流行文化，它只在MoMA上映过一晚。但他的作品也在洛杉矶和旧金山等城市上映，所以如果你住在附近，可以去看他的下一次展映。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
As for his own education: He's weighing whether to enroll in university in England or maybe the U.S. to be closer to Silicon Valley. Or perhaps he'll skip college entirely and just focus on his work. 'I absolutely want to start another company,' he says. 'Serial entrepreneurs get addicted to creation. I want to be passionate. I feel really bad when I'm not doing something new.'
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Trigger Mortis was released on September 8, ahead of the release of the latest Bond film Spectre which is out in cinemas on October 26.
Auto sales: Car sales reach 17 million but manufacturers scramble to adjust capacity as trucks and SUVs soar in popularity. Pressure to hold down corporate fuel averages drives margins on small cars far below break-even.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
James Bond Themes 3. "Skyfall" by Adele
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Cambridge Judge Business School also ends the year on a high, appearing for the first time in the rankings for both open and custom executive education, and climbing three places in the MBA ranking and 12 places in the Executive MBA table.
I wonder if the Pelicans are in that position, too. It looks like their highest Brow-era pick will be Buddy Hield. That's not optimal.
A modular microarray imaging system for highly specific COVID-19 antibody testing
For the first time a Bond girl’s storyline will be followed beyond her fleeting experience with 007, with the return of Pussy Galore.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
位居榜单第三的是史蒂夫·卡瑞尔（Steve Carell）。《卑鄙的我2》（Despicable Me 2）在今年大获成功，斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房，该系列第三部《小黄人》（Minions）也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》（The Way Way Back）和《超级魔术师》（The Incredible Burt Wonderstone）。后一部影片的票房虽未能赚回制作成本，但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。
The movie takes place a year after the events of Finding Nemo and follows the journey of Dory to find her parents. Dory is helped by Nemo and Marlin in this epic adventure along the coast of California. You will also see some new characters introduced in the film.
New construction will provide luxury options for renters with deep pockets, mostly in the boroughs outside Manhattan. In Brooklyn, 6,527 new rental units are expected to hit the rental market next year, nearly twice the 3,802 units anticipated for Manhattan, according to Citi Habitats.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
With all its eccentric beats and bubblegum, Number 1 Angel feels like the purest distillation of the U.K. star's pop brilliance, whether she's working with up-and-coming rapper Cupcakke on "Lipgloss" or collaborating with M? on "3AM (Pull Up)."
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Verification and evaluation should be enhanced before publication, Wang said.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Song “Embrace Happiness”(Kelly Chen)
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
For both, opponents are enemies rather than fellow citizens who think differently.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
I've seen managers not hire a woman because the environment is mostly male, and they're worried that no matter how smart or talented she is, she won't fit in.
They boast two of the biggest fan bases in the world.But it was Shawn Mendes who reigned supreme during the 2017 Europe Music Awards 2017, held inside London's SSE Arena, Wembley, on Sunday night, as Taylor Swift lost out in all five of her categories.
Friends wasn't known for being the most diverse show on television at the time, since the cast was comprised of almost entirely white actors. None of the main characters were anything other than "mainstream." Even the acknowledgement of Ross's first wife Carol being a lesbian was met with jokes about sexuality (mostly from Joey), and sexist comments were frequently incorporated into the script.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
新美国基金会(New America Foundation)高级研究员李?德鲁特曼(Lee Drutman)在一份给Vox的分析文章中指出，在阿肯色州、北卡罗莱纳州和田纳西州，移民人口是1990年的三倍以上。围绕这些变化产生的焦虑或许可以解释共和党为什么在这个阶段更关注限制移民问题，还有这些州的白人投票者们何以压倒性地支持特朗普。
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
5. It's a dog's life for the British
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
The regulator said that “faced with a complex and volatile market environment,” funds had realised gains of only Rmb294.5bn in the first half, a drop of 42.3 per cent.
That an iPhone mini and a LTE license from the Chinese government this year or next could finally persuade China Mobile (CHL), with 700 million subscribers, to cut a deal with Apple.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.
Anti-HIV drug repurposing against SARS-CoV-2
Gary Oldman's first film as director in 20 years, and only his second ever, is a biopic of the pioneering 19th-century photographer Eadweard Muybridge, focusing on the affair between his wife, Flora, and Harry Larkyns, the theatre critic he kills. No casting confirmed, but Oldman had been chasing Ralph Fiennes and Benedict Cumberbatch. The man himself will play Muybridge's prosecutor.
For the first time a Bond girl’s storyline will be followed beyond her fleeting experience with 007, with the return of Pussy Galore.
Length-scale dependence of protein hydration-shell density
3.Pay no attention to those bow-tied etiquette experts you sometimes see on CNN International, telling you how to behave while in Britain. These people are generally of dubious provenance, normally live in California and tend to peddle advice that is either irrelevant or out of date. For example, they will often say that Britons love queuing and are so fond of apologising that they will often say "sorry" even when something isn't their fault. In reality, Britons are just as likely to jump to the front of a queue and then punch the person behind them for coughing. It all depends on how muggy it is.
Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion
Average years of work experience: 11
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
The Family Hub has three internal cameras that connect to your phone to help you see what you do and don't have inside the fridge. So it's basically a $6,000 alternative to classic grocery list written on paper with a pencil.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Issued by the Institute of Social Security Research, Ministry of Human Resources and Social Security, the report shows that the return rate of enterprise employees' pension insurance fund reached 3.1 percent, the highest in seven years.
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